“Mebendazole warning! Phase 2 trial shows hyper-progression of cancer!!!
Thinking of trying Fenbendazole?
I was really excited about it until three people I know with colorectal cancer who were previously stable had aggressive metastasis all in one week. Then I started tracking cases and became very concerned. ***update 2021 after tracking people for a year. Fenbendazole is causing premature death (and not just for colon cancer). If you don’t believe me, just set a timer for every positive progress for 8 months to a year OR go back and see what happened to positive progress cases from a year or two ago.
Here are the results of my research so far.
Drug-Induced Liver Injury in a Patient with Nonsmall Cell Lung Cancer after Self-administration of Fenbendazole Based on Social Media Information.
IL-8 is upregulated further by FB and promotes cancer cell migration and aggressiveness. Problem; IL-8 and its receptor CXCR2 are two of the most significantly upregulated chemokines in colorectal cancer. The third link shows that the bacteria responsible for CRC (fusobacterium) induces IL-8 and causes “robust migrations” of cancer cells aka metastasis. Some bendazoles like Fenbendazole significantly induce IL-8 which could cause aggressive metastasis.
At low doses FB decreases Connexin 32 significantly; Connexins fill gap junctions in the intestines. They are also tumor suppressors. Colorectal cancer is associated with loss of connexin expression. They are critical for extracellular communication.
P450 Fenbendazole upregulates P450. Increased P450 indicates poor prognosis in CRC.. Higher levels of P450 equal less detox and can turn procarcinogens into carcinogens.
In this study FB has been found to promote 33 genes for cancer “In conclusion, we here found 33 genes showing altered expression specific to the early stages of tumor promotion by fenbendazole.” This study showed suppression of PTEN (A major tumor suppresser) and upregulation of many tumor promotors.
Fenbendazole kills Lachnospiraceae (protective of CRC) and most all bacteria hence the diarrhea, Cdiff, gastric pain. If cancer Is driven by bacteria this could provide temp shrinkage then resistance and then a roaring comeback.
Liver Tumor Promoting Effects of Fenbendazole in Rats.
“Since those agents that induce CYP 2B1/2 isozymes and reduce Cx32 in centrilobular hepatocytes have been suggested to be liver tumor promoters, the present results indicate that fenbendazole may be a liver tumor promoter.”
Increased tumor growth in the fenbendazole only treatment group. “Fenbendazole may have tumor-promoting activity in rats at therapeutic dosages (that is, through inhibition of connexin 32 and induction of cytochrome P450 enzymes 1A1 and 1A2).”
We have a gene that makes us more sensitive to Fenbendazole than rats. Rats have to by “humanized” with this gene for comparison in lab studies. There are also slow metabolizers and fast.
There are multiple parabens in the goat dewormer, not sure about other formulations.
MSDS Toxicity data
Liver is the main target but also stomach, kidneys, blood, immune system, and central nervous system were affected.
High doses; renal, encephalomalacia, satellitosis, neuronophagia, perivascular inflammation or gliosis, hyperplasia and congestion of the mesenteric lymph nodes
Cyst formation in lymph nodes, liver mass and/or nodule formation, and testicular masses were reported.
Bone Marrow Hypoplasia Associated With Fenbendazole Administration in a Dog; sudden-onset of fever and malaise with low WBC count and bone marrow hypoplasia. Symptoms resolved in 15 days when Fenbendazole was stopped.
“No effect on tumors in mice our studies provided no evidence that fenbendazole warrants further testing as a potential agent for use in cancer therapy”.
Conclusion; Although the chemical structure of fenbendazole is similar to mebendazole (approved for humans), it works differently. I think we’ll know a lot more about it’s effects on humans in the future and for now I think it’s wise to avoid, especially if you’re stable.
***********2021 update- PHASE 2 TRIAL SHOWS HYPER PROGRESSION WITH MEBENDAZOLE! *****MORE INFO HERE
Here’s a study showing synergy with an antihelmith drug and immunotherapy which could explain Joe Tippin’s success. It’s something to watch if you follow immunotherapy.
It's so hard to believe anything any more. Are those studies real or slanted like they did for ivm and covid. My one hesitation in taking high doses is what does it do to your liver? The li ver is critical in filtering out toxins.
I agree about not being able to trust ANY studies anymore, but what led her to go looking is she tracks long term natural healing cancer survivors and what they did that was successful. She noticed some of her previously stable survivors all of a sudden had cancer growth (unvaccinated) and the only thing they changed was adding fenben so she started looking into it. She is a natural healing proponent, her husband healed naturally from colon cancer so she has a vested interest in this stuff. She thinks many cancers likely have a fungal or parasitic origin so she’s not against the idea.
There are many that hate that I report this and I’m usually vilified, even here for saying use caution, but we have to look at all cases not just the successful ones.
Could nice names like: Imperial College of London or Wellcome Trust be funneling BS for you? Oh Darn, those Brits! they seem so nice with their funny accents.
Said it before and will say it again: use caution with fenbendazole.
Research posted on this site:
https://adventureswithjodi.com/cancer-pathway_charts/
Copied below:
“Mebendazole warning! Phase 2 trial shows hyper-progression of cancer!!!
Thinking of trying Fenbendazole?
I was really excited about it until three people I know with colorectal cancer who were previously stable had aggressive metastasis all in one week. Then I started tracking cases and became very concerned. ***update 2021 after tracking people for a year. Fenbendazole is causing premature death (and not just for colon cancer). If you don’t believe me, just set a timer for every positive progress for 8 months to a year OR go back and see what happened to positive progress cases from a year or two ago.
Here are the results of my research so far.
Drug-Induced Liver Injury in a Patient with Nonsmall Cell Lung Cancer after Self-administration of Fenbendazole Based on Social Media Information.
https://www.karger.com/Article/FullText/516276
aFT3 is induced by FB. aFT3 activation promotes colorectal cancer metastasis.
https://www.ncbi.nlm.nih.gov/pubmed/24859834
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436308
IL-8 is upregulated further by FB and promotes cancer cell migration and aggressiveness. Problem; IL-8 and its receptor CXCR2 are two of the most significantly upregulated chemokines in colorectal cancer. The third link shows that the bacteria responsible for CRC (fusobacterium) induces IL-8 and causes “robust migrations” of cancer cells aka metastasis. Some bendazoles like Fenbendazole significantly induce IL-8 which could cause aggressive metastasis.
https://www.ncbi.nlm.nih.gov/pubmed/20848085 https://www.ncbi.nlm.nih.gov/pubmed/22494524 https://www.biorxiv.org/content/10.1101/2020.01.15.907931v1.full
At low doses FB decreases Connexin 32 significantly; Connexins fill gap junctions in the intestines. They are also tumor suppressors. Colorectal cancer is associated with loss of connexin expression. They are critical for extracellular communication.
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.28911 https://journals.sagepub.com/doi/abs/10.1177/019262339902700509
P450 Fenbendazole upregulates P450. Increased P450 indicates poor prognosis in CRC.. Higher levels of P450 equal less detox and can turn procarcinogens into carcinogens.
https://www.ncbi.nlm.nih.gov/pubmed/21081470
https://journals.sagepub.com/doi/abs/10.1177/01926233990270050
In this study FB has been found to promote 33 genes for cancer “In conclusion, we here found 33 genes showing altered expression specific to the early stages of tumor promotion by fenbendazole.” This study showed suppression of PTEN (A major tumor suppresser) and upregulation of many tumor promotors.
https://academic.oup.com/carcin/article/29/11/2218/2476329
Loss of villus epithelium and stroma within the small intestine of mammals. Passing tissue? Gastric pain?
https://www.ingentaconnect.com/content/aalas/jaalas/2006/00000045/00000006/art00012?crawler=true&fbclid=IwAR2hPPh9GTchD0C2uWcXJXxLot7or0vDUMo–hiIXJpqTeEaXFkEMY22Ino
Korean Doctors warn of intestinal necrosis and severe side effect from taking fenbendazole. Again….passing tumors OR necrotic death of intestines?
https://www.koreabiomed.com/news/articleView.html?idxno=6780&fbclid=IwAR1PosK6viIZd7jPQtey7MKFLfA1e_fZCIQmAzoAAbmMXhCZU6V1d8CZJ7k
Fenbendazole kills Lachnospiraceae (protective of CRC) and most all bacteria hence the diarrhea, Cdiff, gastric pain. If cancer Is driven by bacteria this could provide temp shrinkage then resistance and then a roaring comeback.
https://microbiomeprescription.azurewebsites.net/Library/Modifier?mid2=758
Liver Tumor Promoting Effects of Fenbendazole in Rats.
“Since those agents that induce CYP 2B1/2 isozymes and reduce Cx32 in centrilobular hepatocytes have been suggested to be liver tumor promoters, the present results indicate that fenbendazole may be a liver tumor promoter.”
https://www.ncbi.nlm.nih.gov/pubmed/10528635
Increased tumor growth in the fenbendazole only treatment group. “Fenbendazole may have tumor-promoting activity in rats at therapeutic dosages (that is, through inhibition of connexin 32 and induction of cytochrome P450 enzymes 1A1 and 1A2).”
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687140/
Can cause Immune suppression of B and T cells and long-term severe effects in an autoimmune disease in mice that mimics Multiple Sclerosis.
https://journals.sagepub.com/doi/full/10.1258/la.2010.009148
https://www.ingentaconnect.com/content/aalas/jaalas/2007/00000046/00000006/art00001?crawler=true&mimetype=application/pdf
We have a gene that makes us more sensitive to Fenbendazole than rats. Rats have to by “humanized” with this gene for comparison in lab studies. There are also slow metabolizers and fast.
https://www.ncbi.nlm.nih.gov/pubmed/21081470
There are multiple parabens in the goat dewormer, not sure about other formulations.
MSDS Toxicity data
Liver is the main target but also stomach, kidneys, blood, immune system, and central nervous system were affected.
High doses; renal, encephalomalacia, satellitosis, neuronophagia, perivascular inflammation or gliosis, hyperplasia and congestion of the mesenteric lymph nodes
Cyst formation in lymph nodes, liver mass and/or nodule formation, and testicular masses were reported.
https://www.cvear.com/wp-content/uploads/2012/06/078335976.pdf
Bone Marrow Hypoplasia Associated With Fenbendazole Administration in a Dog; sudden-onset of fever and malaise with low WBC count and bone marrow hypoplasia. Symptoms resolved in 15 days when Fenbendazole was stopped.
https://www.jaaha.org/doi/abs/10.5326/0400224?fbclid=IwAR0ulGIMrGztMnVadeUoOM6eKVetgUn4jLoio0SGgiftdRDByBKPpB_Wplo
Potent interactions with acetaminophen in mice which led to 63% mortality
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262853/
“No effect on tumors in mice our studies provided no evidence that fenbendazole warrants further testing as a potential agent for use in cancer therapy”.
http://ar.iiarjournals.org/content/33/2/355.full
Conclusion; Although the chemical structure of fenbendazole is similar to mebendazole (approved for humans), it works differently. I think we’ll know a lot more about it’s effects on humans in the future and for now I think it’s wise to avoid, especially if you’re stable.
***********2021 update- PHASE 2 TRIAL SHOWS HYPER PROGRESSION WITH MEBENDAZOLE! *****MORE INFO HERE
Here’s a study showing synergy with an antihelmith drug and immunotherapy which could explain Joe Tippin’s success. It’s something to watch if you follow immunotherapy.
https://jitc.biomedcentral.com/articles/10.1186/s40425-019-0733-7?fbclid=IwAR0sXQTqoGGBsOuQFZAOaOLmnmCsf5ojXKyDAODYlFQs_1BuY9ZYpUZySUQ
To print Natural Compounds that Work Similar to Fenbendazole, click here!”
It's so hard to believe anything any more. Are those studies real or slanted like they did for ivm and covid. My one hesitation in taking high doses is what does it do to your liver? The li ver is critical in filtering out toxins.
I agree about not being able to trust ANY studies anymore, but what led her to go looking is she tracks long term natural healing cancer survivors and what they did that was successful. She noticed some of her previously stable survivors all of a sudden had cancer growth (unvaccinated) and the only thing they changed was adding fenben so she started looking into it. She is a natural healing proponent, her husband healed naturally from colon cancer so she has a vested interest in this stuff. She thinks many cancers likely have a fungal or parasitic origin so she’s not against the idea.
There are many that hate that I report this and I’m usually vilified, even here for saying use caution, but we have to look at all cases not just the successful ones.
It's not like Dr.s are being paid to produce fraudulent Peer Reviews or anything. Pharma money? Billy Gaytes money? nah.
oops. 500 Peer Reviewed papers to be RETRACTED:
https://retractionwatch.com/2022/09/28/exclusive-hindawi-and-wiley-to-retract-over-500-papers-linked-to-peer-review-rings/
Could nice names like: Imperial College of London or Wellcome Trust be funneling BS for you? Oh Darn, those Brits! they seem so nice with their funny accents.
I posted a video on Telegram where a doctor addresses that.
Which Telegram? Coffee &Covid?
Yes
Thats why detoxing is important. Taking care of the liver is essential. Here is a protocol worth checking out:https://ourspiritnet.files.wordpress.com/2017/01/ascend-lesson-4-solar-plexus-1.pdf