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Copernicus's avatar

Sugar is one of many things that yes, damages the endothelium. And yes, cholesterol is part of the repair process. Under normal conditions the cholesterol repair gradually is degraded and a smooth endothelial surface is once again present. However, when there is ongoing damage via sugar or other inflammation, then the bandaids accumulate, resulting in clots.

Cholesterol is akin to the fire truck that shows up at the scene of a fire. It’s the response to a problem, not the cause.

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Robin Greer's avatar

Exactly. Thanks for the additional explanation and analogy.

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Copernicus's avatar

Your welcome. The analogy is not original with me.

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